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Over the years, methods have been refined into the most commonly used protocol today, which uses an acid/ethanol precipitation (to disrupt the IGF-1/IGFBP complex) followed by the addition of insulin-like growth factor-2 (IGF-2) to prevent the reformation of the IGF/IGFBP complex
It is now being recognized as the gold standard in collagen because it is tastless, odorless and highly absorbable
Fultz NE, Bonmassar G, Setsompop K, Stickgold RA, Rosen BR, Polimeni JR, et al
Weight loss as monotherapy is minimal, averaging 2-4 additional pounds monthly versus placebo in controlled settings
ISSN 0140-0460
Smith, B
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